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Therapeutic Targeting of PPAR Signaling in Cancer Treatment-Related Lymphedema

J.Y. Kwan, P.A. Bissey, W. Shi,J. Williams,S. Haykal,B. Haibe-Kains,K. Yip,F.F. Liu

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS（2021）

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Abstract
These data, for the first time, demonstrated the value of upregulating PPAR signaling to treat lymphedema. For this condition, which to date, has no cure, repurposing PPAR agonists for lymphedema treatment is a highly promising therapeutic opportunity, which warrants further investigation.
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Key words
therapeutic targeting,ppar,treatment-related
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