18F-Fluciclovine PET/CT to Distinguish Radiation Necrosis From Tumor Progression in Brain Metastases Treated With Stereotactic Radiosurgery: Results of a Prospective Pilot Study

International Journal of Radiation Oncology*Biology*Physics(2021)

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摘要
In this prospective pilot study, F Fluciclovine PET CT demonstrated promising accuracy to distinguish RN from TP among pts with BM previously treated with SRS. Using SUVmax, a cutpoint of 4.3 provided a sensitivity of 1.0 and specificity of 0.63. Confirmatory phase II and III studies are ongoing.
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关键词
stereotactic radiosurgery,brain metastases,distinguish radiation necrosis,f-fluciclovine
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