High SMAD4 Expression is Associated With Better Clinical Outcomes in Patients With Resectable Pancreatic Cancer: An Analysis of NRG Oncology/RTOG 9704

T M Williams, J Moughan,E Ben-Josef, W F Regine, C D Timmers,R Robb,T A DiPetrillo, N C Leasure, R Mowat,H Kim, J M Koenig,S Narayan, D A Bush, M Fromm,C Guha

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS（2021）

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摘要

Tumor expression of SMAD4 is significantly associated with better clinical outcome, specifically lower DM and higher DFS and OS, in tumor samples from a large, phase III randomized trial of resectable pancreatic cancer.

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