How Significant is the Delineation Bias in CT Radiomics Prognostic Power?

A. Romita,I. Zhovannik,A. Dekker,E. Pfaehler,A. Traverso,R. Monshouwer

International journal of radiation oncology, biology, physics（2021）

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Abstract

Radiomic features extracted from routinely delineated GTVs can be biased by the tumor-air edge in CT. Our results show that features extracted from eroded GTVs can achieve better results than the features from the original GTVs. In addition, five features used in our analysis were selected to be unbiased by tumor volume.

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