Antifungal-Loaded Calcium Sulfate Beads as a Potential Therapeutic in Combating Candida auris

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY(2022)

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摘要
Candida auris provides a substantial global nosocomial threat clinically. With the recent emergence that the organism can readily colonize skin niches, it will likely continue to pose a risk in health care units, particularly to patients undergoing surgery. The purpose of this study was to investigate the efficacy of antifungal-loaded calcium sulfate (CS) beads in combatting C. auris infection. We demonstrate that the CS-packed beads have the potential to interfere with planktonic and sessile C. auris.
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关键词
biofilm, fungal, wound management, antimicrobial, Candida auris, antimicrobial activity, calcium sulfate
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