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Effect of alginate nanoparticles on the immunogenicity of excretory-secretory antigens against acute toxoplasmosis in murine model

Maha R Gaafar,Salwa T El-Mansoury,Maha M Eissa,Thanaa I Shalaby,Layla K Younis,Hoda A Rashed

Acta Tropica（2022）

Cited 5|Views7
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Abstract
-Alginate nanoparticles proved its effectiveness in enhancing excretory-secretory antigens.-In vivo-prepared vaccine induced reduction tachyzoite count and viability.-SEM and TEM revealed tachyzoites deformities.-Amelioration of the pathological changes in liver and spleen.
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Key words
Alginate nanoparticles,Excretory-secretory antigens,RH Toxoplasma strain,Immunology,Electron Microscopy,Histopathology
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