Incidence of New-Onset Obstructive Sleep Apnea After Posterior Flap Pharyngoplasty in Children

ANNALS OF PLASTIC SURGERY(2022)

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摘要
Introduction Obstructive sleep apnea (OSA) is a well-recognized complication of velopharyngeal insufficiency (VPI) surgery, but studies assessing OSA by means of a respiratory polygraphy (PG) are scarce. The aim of the study was to evaluate the incidence of new-onset OSA after posterior flap pharyngoplasty (PFP). Materials The postoperative PG of children with VPI who had a normal preoperative PG were analyzed. Results Eighteen patients (mean age, 9.8 +/- 4.8 years; Pierre Robin sequence [n = 5], isolated cleft palate [n = 7], 22q11 deletion [n = 3], and 3 other diagnoses) were included in the study. Mean delay between surgery and the postoperative PG was 11.5 +/- 13.5 months. Two patients (11%) developed severe OSA after PFP. One patient with 22q11 deletion developed overt OSA symptoms immediately after surgery with an apnea-hypopnea index (AHI) of 39 events per hour, requiring continuous positive airway pressure (CPAP) therapy. Obstructive sleep apnea improved spontaneously after 10 months, with an AHI of 2 events/h after CPAP weaning. The second patient had a cleft palate associated with a fetal alcohol syndrome and developed OSA symptoms after surgery with an AHI of 18 events/h requiring CPAP therapy. He could be weaned from CPAP 6 months later after a complete section of the pharyngeal flap with an AHI of 6 events/h during spontaneous breathing. Conclusions New-onset OSA after PFP in children with VPI who had a normal preoperative PG was uncommon (11%) in the present cohort.
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关键词
velopharyngeal insufficiency, posterior flap pharyngoplasty, respiratory polygraphy, obstructive sleep apnea, child
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