Effect of Ramadan fasting on renal function of people with diabetes; a prospective longitudinal study

Aim: To observe the effect of Ramadan fasting on renal function of people with diabetes. Methods: This prospective, observational, and longitudinal study was conducted at Baqai Institute of Diabetology and Endocrinology, between April-July 2019. People with type2 dia-betes mellitus were recruited using convenient sampling. Demographic data along with renal function were recorded before Ramadan. Kidney functions were assessed in those who came for follow up at 6 weeks, 3 months, and a year after Ramadan. Results: A total of seventy people with diabetes participated in this study with the mean age of 53.11 +/- 8.70 years. A significant decline in eGFR was noted around six weeks post Ramadan with a significant improvement of eGFR at 3 months follow-up. The normaliza-tion of kidney functions among the study participants was observed even after one year of Ramadan. Conclusion: In this study post Ramadan assessment of creatinine clearance showed a sig-nificant fall among fasting people with diabetes though remained with in normal limits. Significant improvement and reversal of kidney functions was noted in those who followed within three months' time. (c) 2021 Elsevier B.V. All rights reserved.