A Systematic Review and Meta-Analysis on the Efficacy and Safety of Direct Oral Anticoagulants in Patients with Peripheral Artery Disease
Annals of Vascular Surgery(2022)
Abstract
DOAC use alone or combined with an anti-platelet agent could be associated with lower re-intervention rates, without increasing the risk for adverse bleeding events. However, this study failed to detect any difference in terms of all-cause mortality, MACEs and MALEs between DOAC users and DOAC naïve patients. Future studies are needed to better determine the efficacy and safety of DOACs in patients with PAD.
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Key words
ASA,Antiplatelet,DOAC,Direct Oral Anticoagulants,PAD,Peripheral Artery Disease,Rivaroxaban
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