Brain aging mechanisms with mechanical manifestations

Yana Blinkouskaya,Andreia Caçoilo, Trisha Gollamudi, Shima Jalalian,Johannes Weickenmeier

Mechanisms of Ageing and Development（2021）

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摘要

•Brain aging leads to cerebral atrophy caused by various neurodegenerative processes.•Mechanics allows to relate biological changes to organ-level brain shape changes.•We summarize critical morphological changes and their underlying aging mechanisms.

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关键词

Brain aging mechanisms,Cerebral atrophy,Morphological changes,Gray and white matter changes,Vascular changes

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