Adequacy of samples obtained via percutaneous core-needle rebiopsy for EGFR T790M molecular analysis in patients with non-small cell lung cancer following acquired resistance to first-line therapy: A systematic review and meta-analysis

•While bronchoscopic biopsy methods result in fewer biopsy-related complications, percutaneous core-needle biopsy (PT-CNB) is superior in its ability to obtain more tissue.•Rebiopsies characterizing resistance mutations in patients with non-small cell lung cancer (NSCLC) can guide personalized medicine and improve overall survival rates.•Percutaneous core-needle lung biopsies obtain adequate samples for molecular characterization of the acquired resistance mutation T790M in patients with NSCLC.