A quinoline derived D-A-D type fluorescent probe for sensing tetrameric transthyretin
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS(2021)
摘要
Nowadays, with an upward trend in the prevalence of intracerebral amyloidosis, it is of great significance to use fluorescent probes for early diagnosis in vitro. In this study, a quinoline-derived D-A-D type chemosensor was rationally designed and synthesized as a probe for the sensitive detection of tetrameric transthyretin (WT-TTR).
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关键词
Hereditary TTR amyloidosis, Fluorescent probe, Tetrameric transthyretin
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