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Incorporation of green emission polymer dots into pyropheophorbide-α enhance the PDT effect and biocompatibility

Faiza Sajjad,Hui Jin,Yiping Han,Laixing Wang,Leilei Bao,Ting Chen,Yijia Yan,Yan Qiu,Zhi-Long Chen

Photodiagnosis and Photodynamic Therapy（2022）

Cited 3|Views9
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Abstract
•Photodynamic therapy (PDT) is used for the treatment of cancer.•Incorporation of polymer dots into pyropheophorbide-a (PPa) improves the laser induced effects of PPa.•The conjugated drug inherits the pH sensitivity of polymer dots.•The nano-dugs synthesized through different methods possess good biocompatibility and low toxicity.
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Key words
Photodynamic therapy,Up-conversion photoluminescence,Carbon based polymer dots (CPDs),pH sensitivity,Photosensitizers
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