Evasion of the complement system by Leishmania through the uptake of factor H, a complement regulatory protein

Adalberto Alves Pereira Filho, Alexandre Alves de Sousa Nascimento,Natália Alvim Araújo Saab,Ricardo Toshio Fugiwara,Grasielle Caldas D'Ávila Pessoa,Leonardo Barbosa Koerich,Marcos Horácio Pereira,Ricardo Nascimento Araújo,Mauricio Roberto Viana Sant'Anna,Nelder Figueiredo Gontijo

Acta Tropica（2021）

引用 10|浏览17

暂无评分

摘要

•A new mechanism of complement inhibition by Leishmania has been described.•This mechanism involves the uptake of the regulatory protein factor H.•There is a putative factor H receptor on the parasites surface.•The factor H uptake results in C3b inactivation by factor I on Leishmania surface.

查看译文

关键词

Leishmania,Complement system resistance,Factor H,C3b inactivation,Complement evasion mechanism,GP63

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要