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Transient Receptor Potential Melastatin 2 Thermosensitive Neurons in the Preoptic Area Involved in Menopausal Hot Flashes in Ovariectomized Mice.

Qiyue Yang,Yanrong Sun,Wenjuan Wang,Jing Jia,Wenpei Bai,Ke Wang,Ziyue Wang,Xiaofeng Luo,Hong Wang,Lihua Qin

Neuroendocrinology（2022）

Cited 3|Views6
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Abstract
In menopause, the abnormal quantity and function of TRPM2-TSNs in the POA is key for the development of hot flashes, characterized by an imbalance in heat dissipation and production due to the corresponding imbalance in glutamatergic and GABAergic neurons.
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Key words
GABAergic neuron,Glutamatergic neuron,Hot flashes,Ovariectomy,Transient receptor potential melastatin 2 thermosensitive neuron
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