Comprehensive Gene Expression Signature Using RNA-Seq in Airways of Mouse Model of Severe Asthma with Fungal Sensitization.

Hideki Inoue,Kaho Akimoto,Hitoshi Ikeda,Hiroki Sato,Tomoki Uno,Yoshitaka Uchida,Tomoko Kawahara,Yosuke Fukuda,Kuniaki Hirai,Yoshito Miyata,Tetsuya Homma,Shin Ohta,Mayumi Yamamoto,Shintaro Suzuki,Akihiko Tanaka,Hironori Sagara

International archives of allergy and immunology（2021）

引用 4|浏览32

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摘要

RNA-Seq analysis showed that Alternaria exposure induced inflammatory response and impaired defense mechanisms in mice airway epithelium, which might be therapeutic targets for SAFS.

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关键词

Alternaria,Asthma,Inflammation,Mouse model,RNA-seq

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