Down regulation of tumour biomarkers in colon cancer cells with IRNA PFK-1 plus metformin.

Eduardo Alejandro Reyes Serratos,Elisa Fernandez Castillo, Lizeth Sanchez Lopez,Mauricio Salinas Santander,Danielle Annette Orozco Nunnelly,Monica Gabriela Sanchez Salazar, Enrique Cervantes Astorga, Ana Maria Rivas Estilla,Clara Patricia Rios Ibarra

Journal of B.U.ON. : official journal of the Balkan Union of Oncology(2021)

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摘要
These in vitro results support the potential therapeutic role of metformin and PFK-1 in the treatment of colon cancer via down-modulation of the expression of several important cancer biomarkers.
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