Update on Modulators of Quorum Sensing Pathways inPseudomonas aeruginosa
CURRENT TOPICS IN MEDICINAL CHEMISTRY(2021)
摘要
Modulators of quorum sensing pathways inPseudomonas aeruginosa (PA) gain attention due to their potential therapeutic applications. These chemical agents are viewed as anti -virulence agents capable of increasing the existing therapeutic agents' efficacy against resistant clinical strains. Additionally, they can be utilized in developing anticancer therapeutics, whole-cell biosensors, and artificial biological systems. In this mini-review, we summarize recent (2015-2021) publications on PA's QS modulation.
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关键词
Pseudomonas aeruginosa, virulence factors, quorum sensing, quorum sensing inhibitors
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