Update on Modulators of Quorum Sensing Pathways inPseudomonas aeruginosa

CURRENT TOPICS IN MEDICINAL CHEMISTRY(2021)

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摘要
Modulators of quorum sensing pathways inPseudomonas aeruginosa (PA) gain attention due to their potential therapeutic applications. These chemical agents are viewed as anti -virulence agents capable of increasing the existing therapeutic agents' efficacy against resistant clinical strains. Additionally, they can be utilized in developing anticancer therapeutics, whole-cell biosensors, and artificial biological systems. In this mini-review, we summarize recent (2015-2021) publications on PA's QS modulation.
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关键词
Pseudomonas aeruginosa, virulence factors, quorum sensing, quorum sensing inhibitors
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