The Effect of Self-Paced Exercise Intensity and Cardiorespiratory Fitness on Frontal Grey Matter Volume in Cognitively Normal Older Adults: A Randomised Controlled Trial.

Natalie J Frost,Michael Weinborn,Gilles E Gignac,Ying Xia,Vincent Doré,Stephanie R Rainey-Smith,Shaun Markovic,Nicole Gordon,Hamid R Sohrabi,Simon M Laws,Ralph N Martins,Jeremiah J Peiffer,Belinda M Brown

Journal of the International Neuropsychological Society : JINS（2022）

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摘要

At an aggregate level, six months of self-paced high- or moderate-intensity exercise did not increase frontal GM volume. However, experimentally-induced changes in individual cardiorespiratory fitness was positively associated with frontal GM volume in our sample of older adults. These results provide evidence of individual variability in exercise-induced fitness on brain structure.

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关键词

Brain volume,Cognition,Exercise,Fitness,Intervention,MRI,Physical activity

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