Early immunologic response to mRNA COVID-19 vaccine in patients receiving biologics and/or immunomodulators.

Esteban Rodríguez-Martinó, Rafael Medina-Prieto,Jorge Santana-Bagur, María Santé,Petraleigh Pantoja,Ana M Espino,Carlos A Sariol,Esther A Torres

medRxiv : the preprint server for health sciences（2021）

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摘要

Neutralizing capacity response to the vaccine in subjects was similar to a healthy cohort in spite of lower increases in total IgG antibodies. The CD4 and CD8 results observed may support the capacity to mount an effective cellular response in patients on biologics. Larger studies are needed to determine vaccine efficacy in these patients.

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early immunologic response,immunomodulators,mrna

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