Nocardiosis in Immunocompromised Patients on Alternative Pneumocystis Prophylaxis.

Alfredo G Puing,David J Epstein,Niaz Banaei,Aruna K Subramanian,Anne Y Liu

EMERGING INFECTIOUS DISEASES（2021）

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摘要

Prophylactic trimethoprim/sulfamethoxazole (TMP/SMX) prevents Pneumocystis jirovecii pneumonia and nocardiosis in immunocompromised patients but sometimes is avoided because of purported allergies or side effects. Of 25 immunocompromised patients receiving alternative prophylaxis in whom nocardiosis developed, 16 subsequently tolerated TMP/SMX treatment. Clinicians should consider TMP/SMX allergy evaluation and rechallenging to assess patient tolerance.

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关键词

Nocardia,Pneumocystis jirovecii,bacteria,drug allergy,fungi,immunocompromised,respiratory infections,sulfa,trimethoprim/sulfamethoxazole

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