Sensory-specific peripheral nerve pathology in a rat model of Fabry disease

Tyler B Waltz,Anthony J Burand,Katelyn E Sadler,Cheryl L Stucky

Neurobiology of Pain（2021）

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摘要

•Fabry disease rats exhibit peripheral nerve pathology, specifically in sensory nerves.•Fabry disease tibial nerves exhibit different pathology according to anatomical location.•Fabry disease associated lipids and lysosomes accumulate in peripheral axons.

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关键词

FD,Gb3,α-GAL A,DRG,TEM,LM,IB4,LAMP1

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