Predisposing Factors And Effect Of Bundle Nursing In Picc-Related Upper Extremity Deep Venous Thrombosis In Patients With Non-Hodgkin'S Lymphoma Undergoing Chemotherapy

Objective: To explore the effects of bundle nursing on PICC-related upper extremity deep venous thrombosis (PICC-UEDVT) in patients with non-Hodgkin's lymphoma (NHL) who are undergoing chemotherapy, and contributing factors toward PICC-UEDVT. Methods: 370 NHL patients undergoing chemotherapy in the Department of Hematology were selected prospectively and randomized into a control group (receiving routine nursing) and an observation group (receiving bundle nursing) using random number method. There were 185 patients in each group. The incidence of PICC-UEDVT and satisfaction rate towards nursing were calculated and risk factors for PICC-UEDVT were explored in the two groups. Results: The incidence of PICC-UEDVT was lower in the observation group (18 patients, 9.73%) than that of the control group (35 patients, 18.92%; P<0.05); the satisfaction rate towards nursing was higher in the observation group than the control group (P<0.05). Tumor stage, ECOG score >2, hemoglobin <100 g/L, and D-dimer >0.5 mg/L were factors that contributed to the occurrence of PICC-UEDVT in NHL patients (P<0.05). Conclusion: Tumor stage, ECOG score >2, reduced hemoglobin, and increased D-dimer levels are predisposing factors for PICC-UEDVT in NHL patients. However, bundle nursing can reduce the incidence of PICC-UEDVT and increase the satisfaction rate towards nursing.