The putative role of the relaxin-3/RXFP3 system in clinical depression and anxiety: A systematic literature review

Win Lee Edwin Wong,Gavin Stewart Dawe,Allan H Young

Neuroscience & Biobehavioral Reviews（2021）

引用 4|浏览8

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摘要

•Experimental evidence suggests that RXFP3 activation can reduce depressive- and anxiety-like behavior in rodents.•Acute RXFP3 activation increases food intake in rats.•Some inconsistency exists between pharmacological and genetic studies.•Clear need for more high-quality clinical studies of the relaxin-3/RXFP3 system.

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关键词

Relaxin-3,RXFP3,Neuropeptide,Depression,Anxiety,Neuropsychiatric disorder

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