Stem cell-derived exosomes: A supernova in cosmetic dermatology

JOURNAL OF COSMETIC DERMATOLOGY(2021)

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Abstract
Introduction Stem cell-derived exosomes are cell-free vesicles secreted by stem cells. Exosomes play a pivotal role in cell-to cell communication due to the functional proteins and genetic information which they carry. In addition, studies on cell migration, tumor invasion, tissue regeneration, myocardial repair after injury, and fracture healing have been widely reported. Objectives The purpose of this review is to sum up the current state of research on multiple stem cell-derived exosomes in cosmetic dermatology and to discuss the current challenges and future directions. Methods We searched "skin" and "exosome" from PubMed to find the application of stem cell exosomes in cosmetic dermatology. Results We found that stem cell-derived exosomes have an important place in skin cosmetology such as wound healing, skin aging, and scar formation. Conclusion Stem cell derived exosomes supply a potential tool to cosmetic dermatology. The performance of stem cell derived exosomes in regulating skin physiological and pathobiological functions suggests that stem cell derived exosomes have potential in cosmetic dermatology.
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Key words
cosmetic dermatology, exosome, stem cell-derived
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