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Utilization of Metabolite Identification and Structural Data to Guide Design of Low-Dose IDO1 Inhibitors.

Brett Hopkins,Hongjun Zhang,Indu Bharathan,Derun Li,Qinglin Pu,Hua Zhou,Theodore A. Martinot,Xavier Fradera,Alfred Lammens,Charles A. Lesburg,Ryan D. Cohen,Jeanine Ballard,Ian Knemeyer,Karin Otte,Stella Vincent,J. Richard Miller,Nicolas Solban,Mangeng Cheng,Prasanthi Geda,Nadya Smotrov,Xuelei Song,David Jonathan Bennett,Yongxin Han

ACS Medicinal Chemistry Letters（2021）

Cited 8|Views31
Key words
Indoleamine-2,3,-dioxygenase-1,IDO1,cyclopropylbenzamide,tetrahydronaphthyridine,MetID,PKPD
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