Photocatalytic Fuel Cell-Assisted Molecularly Imprinted Self-Powered Sensor: A Flexible and Sensitive Tool for Detecting Aflatoxin B1

The self-powered electrochemical sensor has gained big achievements in energy and devices, but it is challenging in analytical application owing to its low energy conversion efficiency and limited selectivity caused by the plentiful interference in actual samples. Herein, a new self-powered biosensor was constructed by the integration of a photocatalytic fuel cell (PFC) with a molecular imprinting polymer (MIP) to achieve sensitive and specific detection of aflatoxin B1 (AFB(1)). Compared with other fuel cells, the PFC owns the advantages of low cost, high energy, good stability, and friendly environment by using light as the excitation source. MoS2-Ti3C2Tx MXene (MoS2-MX) served as the photoanode material for the first time by forming a heterojunction structure, which can enhance the photocurrent by about 3-fold and greatly improve the photoelectric conversion efficiency. Aiming at the poor selectivity of the self-powered sensor, the MIP was introduced to achieve the specific capture and separation of targets without sample pretreatment. Using the MIP and PFC as recognition and signal conversion elements, respectively, the proposed self-powered biosensor showed a wide dynamic range of 0.01-1000 ng/mL with a detection limit of 0.73 pg/mL, which opened opportunities to design more novel self-powered biosensors and promoted its application in food safety and environmental monitoring.