Biosynthesis of actarit using engineered Escherichia coli

Daoyi Guo,Xiao Fu,Sijia Kong,Xun Li,Hong Pan

Enzyme and Microbial Technology（2021）

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摘要

•N-acetyltransferase PANAT could catalyse the transfer of an acetyl group from acetyl-CoA to 4-aminophenylacetic acid.•Construction of actarit biosynthetic pathway for the first time in E. coli.•Improving actarit biosynthesis by overexpressing YdiB and AroK.

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关键词

Metabolic engineering,Escherichia coli,N-acetyltransferase,Actarit

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