Leveraging advances in immunopathology and artificial intelligence to analyze in vitro tumor models in composition and space
Advanced Drug Delivery Reviews(2021)
Abstract
•The TME plays a key role in cancer biology and treatment.•In vitro tumor models can mimic the TME to study cancer, but need to be improved.•AI is primed to analyze the data output from tumor models.•AI can characterize the cellular and spatial composition of the TME.•AI can identify novel features and higher order relationships.
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Key words
Machine learning,Deep learning,Tumor models,Immunohistochemistry,Digital pathology,Tumor microenvironment
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