LncRNA KCNQ1OT1 depletion inhibits the malignant development of atherosclerosis by miR-145-5p
Microvascular Research(2022)
摘要
•KCNQ1OT1 is significantly upregulated in AS mice and ox-LDL-treated THP-1 cells.•KCNQ1OT1 silencing ameliorates lipid metabolic disorders and inflammation in AS model.•KCNQ1OT1 acts as a sponge for miR-145-5p.•KCNQ1OT1 silencing suppresses AS progression by upregulating miR-145-5p.
更多查看译文
关键词
KCNQ1OT1,miR-145-5p,Atherosclerosis,Ox-LDL
AI 理解论文
溯源树
样例
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要