Assessing the upper motor neuron in amyotrophic lateral sclerosis using the triple stimulation technique: A multicenter prospective study

Aude-Marie Grapperon,Annie Verschueren,Elisabeth Jouve,Régine Morizot-Koutlidis,Timothée Lenglet,Pierre-François Pradat,François Salachas,Emilien Bernard, Stéphanie Delstanche,Alain Maertens de Noordhout,Nathalie Guy,Véronique Danel,Arnaud Delval,Emilien Delmont,Anne-Sophie Rolland, PULSE Study Group,Laurent Jomir,David Devos,François Wang,Shahram Attarian

Clinical Neurophysiology（2021）

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摘要

•- Triple stimulation technique can be used in routine clinical practice and in multicenter studies in ALS patients.•- Assessment of corticospinal dysfunction at the first visit of the patient was improved by the use of triple stimulation technique compared to conventional TMS.•- Triple stimulation technique results are correlated with the clinical upper motor neuron score and ALSFRS-R.

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关键词

Amyotrophic lateral sclerosis,Upper motor neuron,Transcranial magnetic stimulation,Triple stimulation technique

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