Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Macimorelin in Children with Suspected Growth Hormone Deficiency: An Open-Label, Group Comparison, Dose-Escalation Trial.

Hormone research in paediatrics(2021)

Cited 8|Views5
No score
Abstract
All 3 doses of macimorelin had excellent safety and tolerability with PK/PD profiles in expected ranges. These results support the use of 1.0 mg/mL macimorelin in a Phase 3 test validation trial in children.
More
Translated text
Key words
Drug safety,Drug tolerance,Growth hormone deficiency,Macimorelin,Paediatrics,Pharmacodynamics,Pharmacokinetics,Tolerability
AI Read Science
Must-Reading Tree
Example
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined