Simulated gastrointestinal digestion of cranberry polyphenols under dynamic conditions. Impact on antiadhesive activity against uropathogenic bacteria

Alba Tamargo,Carolina Cueva,Diego Taladrid,Christina Khoo,M Victoria Moreno-Arribas,Begoña Bartolomé,Dolores González de Llano

Food Chemistry（2022）

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摘要

•First simulation of gastrointestinal digestion under dynamic conditions of cranberry polyphenols was carried out.•Cranberry polyphenols degradation led to a diversity of bioaccessible microbial-derived metabolites.•Metabolism of cranberry polyphenols promoted an increase in Enterococcaceae population.•Cranberry metabolism modulated the antiadhesive activity against uropathogenic Escherichia coli.

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关键词

Cranberry,Simgi® model,Polyphenols,Gut microbiota,Metabolism,Phenolic metabolites,Short Chain Fatty Acids (SCFAs),Urinary Tract Infections (UTIs),Antiadhesive activity,Uropathogenic Escherichia coli

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