Moderators of gene-outcome associations following traumatic brain injury

Jai Carmichael,Amelia J. Hicks,Gershon Spitz,Kate Rachel Gould,Jennie Ponsford

Neuroscience & Biobehavioral Reviews（2021）

引用 0|浏览1

暂无评分

摘要

•Traumatic brain injury under complex polygenic influence.•APOE, BDNF, and COMT key genes.•Understanding factors that moderate genetic associations can improve patient care.•Speculative mechanisms of gene-outcome moderation by age, biological sex, ethnicity.•Recommendations for future genetics research in TBI and other populations.

查看译文

关键词

Genetics,Traumatic brain injury,Age,Sex,Ethnicity,Apolipoprotein E,APOE,Brain-derived neurotrophic factor,BDNF,Catechol-O-methyltransferase,COMT,Precision medicine,Antagonistic pleiotropy,Dopamine,Estrogen

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要