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Ethanol extract of Sargarsum fusiforme alleviates HFD/STZ-induced hyperglycemia in association with modulation of gut microbiota and intestinal metabolites in type 2 diabetic mice

Siya Wu,Jihui Zuo,Yang Cheng,Ya Zhang,Zhongshan Zhang,Mingjiang Wu, Yue Yang,Haibin Tong

Food Research International（2021）

Cited 40|Views7
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Abstract
•Ethanol extract (EE) of S. fusiforme alleviated HFD/STZ-induced T2DM.•EE modulated the structure and composition of gut microbiota in T2DM mice.•EE reduced levels of intestinal metabolites BCAA and AAA and increased 4-HPA in T2DM mice.
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Key words
Sargassum fusiforme,Ethanol extract,Gut microbiota,Metabolome,Type 2 diabetic mellitus
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