Development of electrically assisted solvent bar microextraction followed by high performance liquid chromatography for the extraction and quantification of basic drugs in biological samples
Journal of Chromatography A(2021)
Abstract
•Solvent bar microextraction based on aqueous extractant is introduced.•Solvent bar microextraction was coupled with electrically assisted back-extraction.•Basic drugs were determined in human plasma and urine samples.•Efficient sample clean-up was obtained without high dilution of real samples.
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Key words
Basic drugs,Biological sample,Electrically assisted solvent bar microextraction,Plasma,Urine
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