supplementary methods and figures from Mdm2 Is Required for Survival and Growth of p53-Deficient Cancer Cells

File contains supplementary methods, primer sequences, supplementary figures and legends. Supplementary Figure S1 is the confirmation of p53-null status. Supplementary Figure S2 shows loss of Mdm2 induces a G2/M cell cycle arrest. Supplementary Figure S3 shows loss of Mdm2 induces a G2/M cell cycle arrest in vivo. Supplementary Figure S4 shows Mdm2 deletion induces apoptosis in vivo. Supplementary Figure S5 shows gene set enrichment analyses for apoptosis and p53 pathway genes.