Thiolysis of CBD arylethers for development of highly GSH-selective fluorescent probes

Xiaoqiang Tu, Lijun He,Haojie Huang,Haishun Ye,Lu Sun,Long Yi

CHEMICAL COMMUNICATIONS（2021）

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摘要

Thiolysis of 7-cyanobenzoxadiazole (CBD) arylether was investigated for development of GSH-selective fluorescent probes for the first time. The results demonstrate that CBD-based probes have tunable reactivities and appropriate dissociation constants for GSH, and are highly GSH-selective and suitable for bioimaging.

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