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A phase Ib/IIa trial of 9 repurposed drugs combined with temozolomide for the treatment of recurrent glioblastoma: CUSP9v3.

Marc-Eric Halatsch,Richard E Kast,Georg Karpel-Massler,Benjamin Mayer,Oliver Zolk,Bernd Schmitz,Angelika Scheuerle,Ludwig Maier,Lars Bullinger,Regine Mayer-Steinacker,Carl Schmidt,Katharina Zeiler,Ziad Elshaer,Patricia Panther,Birgit Schmelzle,Anke Hallmen,Annika Dwucet,Markus D Siegelin,Mike-Andrew Westhoff,Kristine Beckers,Gauthier Bouche,Tim Heiland

Neuro-oncology advances（2021）

Cited 31|Views15
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Abstract
CUSP9v3 can be safely administered in patients with recurrent GBM under careful monitoring. A randomized phase II trial is in preparation to assess the efficacy of the CUSP9v3 regimen in GBM.
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Key words
chemotherapy,clinical trial ,drug repurposing,glioblastoma,multi-drug combination
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