Antitumor Effect of IL-2 and TRAIL Proteins Expressed by Recombinant Salmonella in Murine Bladder Cancer Cells.

Bruna Dias de Lima Fragelli,Luciana Camillo,Joice Margareth de Almeida Rodolpho,Krissia Franco de Godoy,Cynthia Aparecida de Castro,Patricia Brassolatti,Adilson José da Silva,Ricardo Carneiro Borra,Fernanda de Freitas Anibal

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology（2021）

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摘要

The data presented suggest that IL-2, TRAIL and their MIX proteins in MB49 cells have cytotoxic potential and that this is associated with oxidative stress and apoptosis pathways. These results may contribute to the development of new therapeutic strategies for bladder cancer.

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Salmonella, IL-2, TRAIL, Bladder Tumor, MB49

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