Evaluating the potentials of randomised integrated control trial on tungiasis in a South-western Nigerian community

•The mean of sand fleas decreased from 1.14, 0.07, 0.21, and 1.66 to 0.37, 0.02, 0.09 and 1.08 after two weeks of single spray compared to the untreated location (p <0.001).•The mean lesions of stage I reduced to 0 after 2 to 6 days of 3%, 5%, 10% and 15% ointment application, and stage II and III after 10 to 12 days of 10% and 15% application respectively, and the difference was highly significant.•Notable reduction in severity score of acute and chronic tungiasis was observed thus indicating effectiveness of the topical ointment.