Method performance verification for the combined detection and quantitation of the marine neurotoxins cyclic imines and brevetoxin shellfish metabolites in mussels (Mytilus edulis) and oysters (Crassostrea gigas) by UHPLC-MS/MS

Alison O'Neill,Nadine Morrell,Andrew D Turner,Benjamin H Maskrey

Journal of Chromatography B（2021）

引用 6|浏览2

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摘要

•Single-laboratory validation for eight cyclic imines and two brevetoxin analogues.•Sensitive, specific and rapid extraction and UHPLC-MS/MS method.•Applicable to common shellfish species oysters and mussels.

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关键词

Brevetoxins,Cyclic imines,Marine toxins,Mass spectrometry,Validation,Ammonium fluoride

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