Comparison of Interferon-α-based therapy and nucleos(t)ide analogs in preventing adverse outcomes in patients with chronic hepatitis B

Qian-Guo Mao,Hui-Qing Liang,Ya-Lin Yin,Jin-Mo Tang,Jia-En Yang,Chun-Cheng Wu,Yue Chen,Man-Ying Zhang,Yao-Yu Liu,Xiao-Ting Zheng,Lin-Yi Zhuang,Shao-Dong Chen

Clinics and Research in Hepatology and Gastroenterology（2022）

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摘要

•IFN-α-based therapy was superior to NAs in preventing adverse outcomes in patients with CHB.•IFN-α in preventing HCC was more significant in patients with high-risk HCC.•IFN-α-based treatment was independently associated with a lower adverse outcomes incidence.

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关键词

Chronic Hepatitis b,Hepatocellular carcinoma,Interferon-alpha,Nucleoside analogs,Antivirals

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