Review of Phase III Clinical Trials Outcomes in Patients with Secondary Progressive Multiple Sclerosis

Matthew Mcadams,James M. Stankiewicz,Howard L. Weiner,Tanuja Chitnis

Multiple Sclerosis and Related Disorders（2021）

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摘要

•Secondary Progressive Multiple Sclerosis phase three trials have had mixed results.•Many of the successful trials appear to be driven by treating inflammation.•Patient selection for these trials may explain their outcomes.•Successful measures from phase 3 trials and potential new measures are discussed.

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关键词

Secondary Progressive Multiple Sclerosis,Clinical Trials

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