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Lysine Acetylation Restricts Mutant IDH2 Activity to Optimize Transformation in AML Cells.

Dong Chen,Siyuan Xia,Rukang Zhang,Yuancheng Li,Christopher A. Famulare,Hao Fan,Rong Wu,Mei Wang,Allen C. Zhu,Shannon E. Elf,Rui Su,Lei Dong,Martha Arellano,William G. Blum, Hui Mao,Sagar Lonial,Wendy Stock,Olatoyosi Odenike,Michelle Le Beau,Titus J. Boggon,Chuan He,Jianjun Chen,Xue Gao,Ross L. Levine,Jing Chen

Molecular Cell（2021）

引用 17|浏览49
关键词
mutant IDH2,2-HG,AML,K413 acetylation,FLT3,ACAT1,SIRT3,dimerization
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