The role of sonic hedgehog homologue signal pathway in hypospadias aetiology

Mehmet Saraç,Şenay Canpolat,Ebru Önalan Etem,Ahmet Tektemur,Tugay Tartar,Unal Bakal,Ahmet Kazez

Journal of Pediatric Urology（2021）

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摘要

Genes involved in the SHH pathway might play a role in the aetiology of hypospadias. Furthermore, there is a correlation between molecular defects in this pathway and severity of hypospadias.

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关键词

Hypospadias,Molecular,Genetics,Sonic hedgehog,Patched homolog 1,Glioma-associated oncogene homolog 2

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