PpSP32-like protein as a marker of human exposure to Phlebotomus argentipes in Leishmania donovani foci in Bangladesh

Petra Sumova,Chizu Sanjoba,Laura Willen,Nikola Polanska,Yoshitsugu Matsumoto,Eisei Noiri,Shyamal Kumar Paul,Yusuf Ozbel,Petr Volf

International Journal for Parasitology（2021）

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摘要

•Phlebotomus argentipes is a sole vector of Leishmania donovani in the Indian subcontinent.•40% of humans in the study area have IgG antibodies against P. argentipes saliva.•A correlation was found between IgG responses against P. argentipes saliva and rPagSP06.•rPagSP06 is a valid antigen to measure human exposure to P. argentipes.

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关键词

Phlebotomus argentipes,Leishmania donovani,Salivary glands,Marker of exposure,IgG antibodies,Bangladesh

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