4h-pyrrolo[3,2-c]pyridin-4-one derivatives

user-6073b1344c775e0497f43bf9(2016)

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摘要
Compounds of formula (I) for use in the treatment or prophylaxis of a disease, which is a hyperproliferative disease and/or a disorder responsive to induction of cell death, selected from a haematological tumour, a solid tumour and/or metastases thereof, said tumour harbouring a mutant EGFR with exon 19 or 21 mutations, and their use as pharmaceuticals.
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关键词
Exon,Mutant,Cancer research,Programmed cell death,Disease,Chemistry,Solid tumour
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