Balancing Properties with Carboxylates: A Lead Optimization Campaign for Selective and Orally Active CDK9 Inhibitors
Yunsong Tong,Alan S. Florjancic,Rick F. Clark,Chunqiu Lai,Anthony Mastracchio,Gui-dong Zhu,Morey L. Smith,Peter J. Kovar,Bailin Shaw,Daniel H. Albert,Wei Qiu,Kenton L. Longenecker, Xiaoqin Liu,Amanda M. Olson,Donald J. Osterling,Stephen K. Tahir,Darren C. Phillips,Joel D. Leverson,Andrew J. Souers,Thomas D. Penning ACS medicinal chemistry letters（2021）
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CDK9,kinase inhibitors,carboxylates,lead optimization
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