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Impact of Previous Coronavirus Disease 2019 on Immune Response After a Single Dose of BNT162b2 Severe Acute Respiratory Syndrome Coronavirus 2 Vaccine

Maria Velasco,Maria Isabel Galan,Maria Luisa Cases,Elia Perez-Fernandez,Diana Martinez-Ponce,Beatriz Gonzalez-Pineiro,Virgilio Castilla,Carlos Guijarro

OPEN FORUM INFECTIOUS DISEASES（2021）

Cited 13|Views7
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Abstract
Immune response after a single dose of BNT162b2 vaccine was markedly increased in subjects with previous severe acute respiratory syndrome coronavirus 2 infection, reaching similar immunoglobulin titers to those elicited by the full 2 doses in naive cases, and increased modestly after the second dose. These data may inform the priority of the boosting dose.
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COVID-19,health care workers,immune response,SARS-CoV-2,vaccine
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